CRISPR joins battle of the bulge, fights obesity without edits to genome

A weighty new study shows that CRISPR therapies can cut fat without cutting DNA. Researchers describe how a modified version of CRISPR was used to ramp up the activity of certain genes and prevent severe obesity in mice with genetic mutations that predispose them to extreme weight gain. Importantly, the researchers achieved long-lasting weight control without making a single edit to the genome.

Large restaurant portions a global problem, study finds

A multi-country study finds that large portion sizes in fast food and full service restaurants is not a problem unique to the US. The researchers found that 94 percent of full service meals and 72 percent of fast food meals studied in five countries contained 600 calories or more.

Excess body weight responsible for nearly 4 percent of cancers worldwide

Excess body weight accounted for approximately 3.9 percent of all cancers worldwide in 2012, a figure that is expected to rise in the coming decades given current trends.

Fighting obesity: Could it be as plain as dirt?

It costs the global economy an estimated US $2 trillion annually and has been dubbed a modern day health epidemic, but new research has unearthed a possible cure for obesity -- and it is as plain as dirt!

Your weight history may predict your heart failure risk

In a medical records analysis of information gathered on more than 6,000 people, researchers conclude that simply asking older adult patients about their weight history at ages 20 and 40 could provide real value to clinicians in their efforts to predict patients' future risk of heart failure, heart attacks or strokes.

New review of scientific studies confirms food cravings can be reduced

Food craving, the intense desire to eat certain foods, can sabotage efforts to maintain healthy eating habits and body weight, no matter the time of year. However, an examination of 28 current peer-reviewed scientific studies largely substantiates findings that changes in diet, prescription medications, physical activity and bariatric surgery reduce craving.

BMI is a good measure of health after all, new study finds

A new study supports body mass index as a useful tool for assessing obesity and health.

A correlation between obesity and income has only developed in the past 30 years

It is well known that poorer Americans are more likely to be obese or suffer from diabetes; there is a strong negative correlation between household income and both obesity and diabetes. This negative correlation, however, has only developed in the past 30 years, according to researchers. Since 1990, the rise of obesity and diabetes was fastest among the poorest US regions.

Study links frequent red meat consumption to high levels of chemical associated with heart disease

Researchers have identified another reason to limit red meat consumption: high levels of a gut-generated chemical called trimethylamine N-oxide (TMAO), that also is linked to heart disease. Scientists found that people who eat a diet rich in red meat have triple the TMAO levels of those who eat a diet rich in either white meat or mostly plant-based proteins, but discontinuation of red meat eventually lowers those TMAO levels.

New evidence that females might benefit most from a low-salt diet

A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.

Reducing variations in feeding practices and fortifying breast milk helps micro-preemies grow

Standardizing feeding practices, including the timing for fortifying breast milk and formula with essential elements like zinc and protein, improves growth trends for the tiniest preterm infants, according to new research.

Obesity, risk of cognitive dysfunction? Consider high-intensity interval exercise

Researchers have discovered what might be an effective strategy to prevent and combat cognitive dysfunction in obese individuals. They are the first to examine the modulatory role of an exercise-induced protein in the brain that promotes neuron survival and used high-intensity interval exercise (HIIE) in obese and normal-weight subjects. Obesity reduces the expression of this protein and lower levels are associated with Alzheimer's, Parkinson's and obesity. HIIE upregulated this protein in the obese subjects compared to normal-weight subjects.

Diabetes remission predictors in bariatric surgery

Researchers have improved a standard bariatric surgery clinical scoring system (DiaRem) to extend the prediction time for diabetic remission following bariatric (weight-loss) surgery.

What's behind Mediterranean diet and lower cardiovascular risk?

A new study offers insights from a cohort study of women in the U.S. who reported consuming a Mediterranean-type diet.

DDT in Alaska meltwater poses cancer risk for people who eat lots of fish

Children in Alaska whose diet includes a lot of fish from rivers fed by the Eastern Alaska Mountain Range may have a long-term elevated risk for cancer because of insecticides -- including DDT -- in the meltwater.